Alpha as a Predictive Biomarker

Completed · Not applicable

Conditions studied: Pain

In brief

The investigators will use non-invasive recordings of brain activity to measure pain as a proxy to self-report. Participants will undergo testing for about 3 hours on two separate days. The testing will involve experiencing painful heat.

Key facts

Study ID

NCT02796625

Run by

University of Maryland, Baltimore

People needed

80

Starts

2016-07-01

Expected to finish

2018-07-01

Last updated by the study team

2021-08-11

Who can join

Age: 21 and older, up to 44. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Able to speak, read, and write English
• Between 21 and 44 years of age
• Able to understand and willing to comply with all study procedures and is available for the duration of the study
• Free of an acute or chronic pain condition
• Not history of psychiatric or neurologic condition

You may not qualify if…

• Unable to undergo EEG, assessed on an individual basis
• History of unstable major psychiatric disorder (self-report)
• History of chronic pain (self-report)
• More than 14 alcoholic drinks per week on average (self-report)
• Active [within 6 months] substance or alcohol abuse (self-report and urine toxicology)
• Use of opioids (self-report and urine toxicology)
• History of major depressive disorder (self-report)
• Pregnant or Lactating (women only), based on (self-report and urine test)
• Anything that, in the opinion of the investigator, would place the subject at increased risk or preclude the subject's full compliance with or completion of the study
• Uncontrolled (systolic blood pressure > 175 mmHg or diastolic blood pressure >105 mmHg) or unstable hypertension

Where it is running

• University of Maryland School of Dentistry — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

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