Periodontal Inflammation and Immunity in Preclinical Rheumatoid Arthritis

Completed

Conditions studied: Rheumatoid Arthritis, Periodontal Disease

In brief

The purpose of this study is to evaluate the association of Rheumatoid Arthritis (RA)-related antibodies and periodontal inflammation in subjects at-risk for Rheumatoid Arthritis. Subjects will undergo periodontal and joint examinations, as well as collection of body fluids to measure Rheumatoid Arthritis-related antibodies.

Key facts

Study ID

NCT02794012

Run by

University of Colorado, Denver

People needed

146

Starts

2016-07-01

Expected to finish

2017-12-01

Last updated by the study team

2018-01-09

Who can join

Age: 18 and older, up to 99. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Rheumatoid Arthritis-antibody positivity (anti-CCP) in the absence of arthritis or
• Early RA <36 months since diagnosis

You may not qualify if…

• Pregnancy
• Antibiotic use prior to dental procedures or cleanings
• Wear dentures
• <18 years old

Where it is running

• Barbara Davis Center — Aurora, Colorado, United States

Full record on ClinicalTrials.gov

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