Diagnostic Value of Passive Leg Raise Induced Changes in Carotid Artery Flow Time to Predict Fluid Responsiveness in Critically Ill Patients

Completed · Not applicable

Conditions studied: Fluid Responsiveness, Carotid Artery Flow Time, Passive Leg Raise

In brief

Difficulties in the accurate assessment of intravascular volume in critically ill patients are frequently encountered. In addition to clinical evaluation, bedside echocardiographic measurements of fluid responsiveness can be technically difficult, especially in critically ill mechanically ventilated patients. The carotid artery is an easily accessible structure that is amenable to bedside ultrasonography performed by Intensivists. The investigators hypothesize that measurement of the carotid artery Corrected Flow Time (FTC) in response to a passive leg raise (PLR), which simulates a fluid bolus, can be used to predict fluid responsiveness.

Key facts

Study ID

NCT02789124

Run by

University of Louisville

People needed

22

Starts

2014-06-01

Expected to finish

2015-11-01

Last updated by the study team

2016-06-09

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18 or older,
• admitted to ICU and already have an arterial line and Flotrac/Vigileo monitor in place ordered by primary team as part of their clinical standard practice.

You may not qualify if…

• Not in sinus rhythm,
• clinically suspected or known intraabdominal hypertension,
• lower extremity amputee,
• femoral arterial line,
• poor or unreliable arterial line waveform,
• history of carotid endarterectomy in the artery being measured,
• pregnancy

Where it is running

• University of Louisville — Louisville, Kentucky, United States

Full record on ClinicalTrials.gov

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