Aerobic Exercise and Cognitive Training in Older Adults

Completed · Not applicable

Conditions studied: Sedentary Lifestyle

In brief

The purpose of this study is to examine the impact of a combined cognitive training and aerobic exercise intervention in sedentary older adults. It is hypothesized that the aerobic exercise will potentiate and increase the generalizability of the cognitive training. Importantly, this study will focus on older adults at-risk for mobility disability. This area is of particular importance considering a large percentage of adults are entering old age and therefore likely to suffer from age-related cognitive decline and mobility disability. To address the investigators' research question 60 adults (age 18-89) will be randomized to one of two 12 week intervention groups: 1) Cognitive Training alone (CT) or 2) Aerobic Exercise + Cognitive Training (AE+CT). The aerobic exercise arm of the study will follow the same format shown to improve a broad range of executive functions in older adults in previous research. The cognitive training arm will consists of a popular commercially-available brain fitness program that has demonstrated specific cognitive improvements and high adherence.

Key facts

Study ID

NCT02787655

Run by

VA Office of Research and Development

People needed

78

Starts

2013-02-01

Expected to finish

2019-06-01

Last updated by the study team

2020-11-16

Who can join

Age: 18 and older, up to 89. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Right handed
• English speaking
• Aged 18 to 89
• Sedentary as defined by < 120 min/week of aerobic exercise over prior 3 months
• Non-demented (MMSE 24)

You may not qualify if…

• Severe diabetes requiring insulin
• Cognitive-executive function deficit (MoCA < 26)

Where it is running

• Atlanta VA Medical and Rehab Center, Decatur, GA — Decatur, Georgia, United States

Full record on ClinicalTrials.gov

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