Prophylactic Pregabalin to Decrease Pain During Medical Abortion

Completed · Phase 4 · Has a placebo group

Conditions studied: Acute Pain

In brief

Medical abortion has been associated with significant pain. The objective of this trial is to determine whether one dose of pregabalin 300 mg, given during medical abortion in addition to the standard of care analgesics, will decrease experienced pain. Investigators will perform a randomized, double-blinded, placebo-controlled trial. Participant pain levels and side effects will be assessed at multiple time points, along with a measure of satisfaction.

Key facts

Study ID

NCT02782169

Run by

University of Hawaii

People needed

110

Starts

2015-06-01

Expected to finish

2016-12-01

Last updated by the study team

2018-04-19

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Requested and consented for pregnancy termination by medical abortion
• Willing and able to complete multiple electronic surveys

You may not qualify if…

• Previous participation in this trial
• Current use of pregabalin or gabapentin
• Contraindication to medical abortion with mifepristone and misoprostol
• Contraindication or allergy to ibuprofen, oxycodone, acetaminophen, or pregabalin
• Unable to understand and sign written informed consents in English

Where it is running

• Women's Options Center — Honolulu, Hawaii, United States

Full record on ClinicalTrials.gov

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