Diffusion-Weighted MRI for Liver Metastasis

Completed

Conditions studied: Colorectal Cancer, Colon Cancer Liver Metastasis, Malignant Neoplasm of Rectum Metastatic to Liver

In brief

The DREAM study will assess the diagnostic accuracy of diffusion-weighted MRI in combination with other imaging modalities (multiparametric MRI and CT Scan) in determining the true status of disappearing liver metastasis (DLM) detected after conversion systemic therapy for unresectable or borderline resectable colorectal liver metastasis (CRLM).

Key facts

Study ID

NCT02781935

Run by

European Organisation for Research and Treatment of Cancer - EORTC

People needed

233

Starts

2016-11-01

Expected to finish

2023-09-27

Last updated by the study team

2024-01-05

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may not qualify if…

• Contraindications to any contrast agents for CT and MRI or MRI procedure
• Pregnancy
• Significant comorbidity that will preclude either conversion therapy or surgery

Where it is running

• OHSU Knight Cancer Institute — Portland, Oregon, United States
• The University of Texas MD Anderson Cancer Center — Houston, Texas, United States
• Innsbruck Universitaetsklinik — Innsbruck, Austria
• Universitair Ziekenhuis Gent — Ghent, Belgium
• U.Z. Leuven - Campus Gasthuisberg — Leuven, Belgium
• Institut Bergonie — Bordeaux, France
• Centre Leon Berard — Lyon, France
• Gustave Roussy — Villejuif, France
• Chiba Cancer Center — Chiba, Japan
• Gifu University Hospital — Gifu, Japan
• Hiroshima Prefectural Hospital — Hiroshima, Japan
• Hyogo College of Medicine — Hyōgo, Japan
• Niigata Prefectural Cancer Center Hospital — Niigata, Japan
• Osaka Medical Center for Cancer and Cardiovascular Diseases — Osaka, Japan
• Gunma Cancer Center — Ōta-ku, Japan
• Jichi Medical University Saitama Medical Center — Saitama, Japan
• Shizuoka Cancer Center — Shizuoka, Japan
• National Cancer Center Hospital — Tokyo, Japan
• Tokyo Medical and Dental University — Tokyo, Japan
• Yamagata Prefectural Central Hospital — Yamagata, Japan
• Kanagawa Cancer Center — Yokohama, Japan

Full record on ClinicalTrials.gov

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