A Safety, Efficacy and Pharmacokinetic Study of AGN-199201 and AGN-190584 in Patients With Presbyopia

Completed · Phase 2

Conditions studied: Presbyopia

In brief

This is a safety, efficacy and pharmacokinetics study of the fixed combination of AGN-199201 and AGN-190584 in participants with presbyopia (inability to focus on items close-up).

Key facts

Study ID

NCT02780115

Run by

Allergan

People needed

151

Starts

2016-05-26

Expected to finish

2017-10-31

Last updated by the study team

2020-12-22

Who can join

Age: 40 and older, up to 55. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Normal vision at distance, either natural or post corneal laser refractive surgery, with presbyopia in each eye and complaints of poor near vision that impacts activities of daily living

You may not qualify if…

• Use of any topical ophthalmic medications, including artificial tears other than the study medications during the study
• Corneal abnormalities in either eye that interfere with visual acuity
• History of cataract surgery, phakic intraocular lens surgery, corneal inlay surgery or any intraocular surgery
• Diagnosis of glaucoma or ocular hypertension.

Where it is running

• Retina Institute of California Medical Group — Arcadia, California, United States
• Sall Research Medical Center — Artesia, California, United States
• WCCT Global, LLC — Cypress, California, United States
• Specialty Eye Care Medical Center — Glendale, California, United States
• Lugene Eye Institute — Glendale, California, United States
• The Eye Research Foundation — Newport Beach, California, United States
• Stanford Eye and Laser Center — Palo Alto, California, United States
• Wolstan and Golberg Eye Associates — Torrance, California, United States
• MedEye Associates — Miami, Florida, United States
• Central Florida Eye Institute — Ocala, Florida, United States
• Center for Sight — Sarasota, Florida, United States
• Clayton Eye Center — Morrow, Georgia, United States
• Silverstein Eye Centers — Louisville, Kentucky, United States
• The Eye Care Institute — Louisville, Kentucky, United States
• Specialized Eye Care — Baltimore, Maryland, United States
• James D. Branch — Winston-Salem, North Carolina, United States
• Devers Eye Institute — Portland, Oregon, United States
• Scott & Christie and Associates, PC — Cranberry Township, Pennsylvania, United States
• Medical University of South Carolina — Charleston, South Carolina, United States
• Total Eye Care, PA — Memphis, Tennessee, United States
• Cataract and Glaucoma Center — El Paso, Texas, United States
• University of Texas Medical Branch — Galveston, Texas, United States
• R and R Eye Research, LLC — San Antonio, Texas, United States
• Medical Center Ophthalmology Associates — San Antonio, Texas, United States
• Hoopes Durrie Rivera Research, LLC — Draper, Utah, United States

Full record on ClinicalTrials.gov

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