Biomarker Study in Participants With Migraine

Completed · Early Phase 1

Conditions studied: Migraine Disorders

In brief

This is a study of participants with a diagnosis of migraine who completed another clinical trial NCT02163993. The participants received either LY2951742 or placebo. This study NCT02766517 will evaluate how certain biomarkers may be related to the participant's response in study NCT02163993. The study will last about five days.

Key facts

Study ID

NCT02766517

Run by

Eli Lilly and Company

People needed

37

Starts

2016-09-28

Expected to finish

2017-01-01

Last updated by the study team

2019-04-09

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Participants with migraine who have previously participated in study NTC02163993 and received one of the selected doses of galcanezumab or placebo
• Have suitable skin characteristics for the dermal capsaicin challenge

You may not qualify if…

• Have a history of significant allergies, in particular to ethanol or sensitivity to the fruits of capsicum plants (for example, chili peppers)
• Have eczema, scleroderma, psoriasis, dermatitis, keloids, tumors, ulcers, burns, flaps, or grafts on their forearm or other abnormality of the skin which may interfere with the study assessments
• Cannot avoid excess tanning (any exposure to sunlight or a tanning bed which would cause a sunburn reaction) throughout the study and cannot cover forearms for 24 hours prior to each treatment period
• Have excessive hair growth on the volar surface of the forearm or participants currently using lotions, oils, depilatory preparations, or other topical treatments on a regular basis which cannot be discontinued for the duration of the study; has used any topical treatments within 7 days of the start of the study

Where it is running

• Arizona Research Center — Phoenix, Arizona, United States
• Pharmacology Research Institute, Newport Beach — Encino, California, United States
• Parexel Early Phase Unit at Glendale — Glendale, California, United States
• Pharmacology Research Institute, Newport Beach — Los Alamitos, California, United States
• Pharmacology Research Institute, Newport Beach — Newport Beach, California, United States
• Medical Center for Clinical Research — San Diego, California, United States
• California Clinical Trials — San Diego, California, United States
• Avail Clinical Research LLC — DeLand, Florida, United States
• Psychiatric Inst of Florida-Clinical Neuroscience Solutions — Orlando, Florida, United States
• PharmaSite Research Inc — Baltimore, Maryland, United States
• PAREXEL-Phase 1 Baltimore Harbor Hospital Center — Baltimore, Maryland, United States
• Rochester Clinical Research, Inc. — Rochester, New York, United States
• CNS Health Care — Memphis, Tennessee, United States
• Northwest Clinical Research Center — Bellevue, Washington, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.