Transcranial Direct Current Stimulation (TDCS) for Auditory Hallucinations in Early Onset Schizophrenia (EOS)
Stopped early · Not applicable
Conditions studied: Schizophrenia
In brief
Youths diagnosed with early onset schizophrenia will demonstrate amelioration of auditory hallucinations after one week of twice daily treatment with transcranial direct current stimulation (tDCS).
Key facts
- Study ID
- NCT02764164
- Run by
- Children's Hospital Medical Center, Cincinnati
- People needed
- 1
- Starts
- 2015-01-01
- Expected to finish
- 2016-08-01
- Last updated by the study team
- 2021-03-05
Who can join
Age: 8 and older, up to 25. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Structured Clinical Interview for Diagnostic and Statistical Manual (DSM) Disorders (SCID) primary diagnosis of DSM-IV (Diagnostic and Statistical Manual of Mental Disorders-Version IV) schizophrenia or schizoaffective disorder
- Ages 8 to 25 years-old
- Persistent auditory hallucinations
- Full Scale intelligent quotient (IQ) greater than 60.
- Stable antipsychotic medication for > 4 weeks
- If female and not infertile patient must agree to use one of the following forms of contraception for the duration of study participation: systemic hormonal treatment or an interuterine device (IUD).
- Legal guardian has provided written informed consent and the subject has provided written informed assent when able. Expectation that a majority of subjects will be able to assent but the potential for the younger children and/or those that are of borderline intellectual functioning will not be able to assent.
You may not qualify if…
- History of alcohol, substance dependence or abuse in the past 90 days
- Open skin wounds that would preclude use of TDCS electrodes
- If female, pregnancy or breast feeding, as determined during eligibility pre-screen call
- Subjects exhibiting significant ongoing severe disruptive, aggressive, self-injurious, or sexually inappropriate behavior will not be eligible for enrollment.
- Presence of any medical condition that would make treatment with tDCS less safe. This includes any implanted metal device or any cardiac pacemaker. Subjects with a history of a seizure disorder are permitted if the subject has been seizure free for 6 months and is currently treated with an anticonvulsant that has been stable for 4 weeks.
- Presence of any other condition that would make the participants unable to comply with the requirements of the study for any reason. This may include an appreciable hearing or visual impairment.
Where it is running
- Cincinnati Children's Hospital Medical Center — Cincinnati, Ohio, United States
Full record on ClinicalTrials.gov
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