Analysis of Oncogenes in Intrahepatic Cholangiocarcinoma or Mixed Hepatocellular-Cholangiocarcinoma in Tumor Tissue Samples
Completed
Conditions studied: Intrahepatic Cholangiocarcinoma, Mixed Hepatocellular Cholangiocarcinoma, Cholangiocarcinoma
In brief
The primary objective of this study is to estimate the frequency of FGFR2 fusions in archived intrahepatic cholangiocarcinoma (iCCA) or mixed hepatocellular-cholangiocarcinoma (HCC-CCA) tumor samples
Key facts
- Study ID
- NCT02762721
- Run by
- ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA)
- People needed
- 131
- Starts
- 2016-06-06
- Expected to finish
- 2017-04-06
- Last updated by the study team
- 2017-06-08
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- If required by law or local regulations (i.e., the sample is from an identifiable subject), signed written informed consent should be granted prior to use of the sample in the study
- ≥ 18 years of age
- Histologically or cytologically confirmed iCCA or mixed HCC-CCA, who are/were eligible for systemic therapy (samples collected prior to initiation of the systemic therapy may be submitted for testing)
- Have one or more formalin fixed and paraffin embedded blocks available. If blocks are not evaluable, 7-10 unstained, non-baked slides with 5-micron thick sections with at least 20% tumor tissue should be available. (Potential participants who are scheduled to undergo surgical treatment may agree to provide surplus of tissues not required for diagnosis and have to provide informed consent prior to the surgery.)
You may not qualify if…
- Not applicable: Patients must meet all of the inclusion criteria.
Where it is running
- Study site — Atlanta, Georgia, United States
- Study site — Seattle, Washington, United States
- Study site — Rozzano, MI, Italy
- Study site — Benevento, Italy
- Study site — Milan, Italy
- Study site — Pisa, Italy
Full record on ClinicalTrials.gov
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