Effects of EED on Zn Absorption and Retention in Children From a Standard Dose

Completed

Conditions studied: Environmental Enteric Dysfunction, Zinc Deficiency, Vitamin A Deficiency

In brief

The overall objective is to determine the impact of EED on zinc absorption and homeostasis, and its impact on the absorptive capacity of vitamin A absorption of young children (18-24 months of age) in an austere setting with high rates of diarrhea, stunting, and micro-nutrient deficiencies.

Key facts

Study ID

NCT02760095

Run by

University of Colorado, Denver

People needed

46

Starts

2015-11-01

Expected to finish

2017-06-01

Last updated by the study team

2019-07-01

Who can join

Age: 2 and older, up to 2. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Absence of apparent health problems that would impair ability to consume regular diet, to tolerate zinc supplements, or to comply with demands of metabolic studies
• Length for age Z-score (LAZ) between -1.5 to -3.0
• Hemoglobin (Hgb) ≥ 8

You may not qualify if…

• Outside age range
• Hgb < 8
• Chronic illness
• Recent diarrhea (within past 2 weeks, treated with supplemental zinc)
• Severe stunting and/or severe acute malnutrition (SAM): LAZ <-3; Weight-for-age Z-score (WHZ) <-3 or mid-upper arm circumference (MUAC) < 115 or edema

Where it is running

• University of Colorado Denver School of Medicine — Aurora, Colorado, United States
• icddr,b (International Centre for Diarrheal Disease Research, Bangladesh — Dhaka, Bangladesh

Full record on ClinicalTrials.gov

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