Evaluating the Neurobiological Basis of Traumatic Dissociation in Women With Histories of Abuse and Neglect

Enrolling by invitation

Conditions studied: Posttraumatic Stress Disorders, Dissociative Identity Disorder

In brief

This study aims to evaluate the neurobiological basis of traumatic dissociation in a cross-diagnostic sample of women who have histories of childhood abuse and neglect.

Key facts

Study ID

NCT02757339

Run by

Mclean Hospital

People needed

200

Starts

2015-06-01

Expected to finish

2027-06-01

Last updated by the study team

2026-06-25

Who can join

Age: 18 and older, up to 89. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Female
• Clinical diagnosis of PTSD or DID and history of childhood abuse, or healthy controls
• Age between 18 and 89
• Legal and mental competency of the patient

You may not qualify if…

• Male
• Under 18 or over 89
• Legal or mental incompetence
• Delirium secondary to medical illness
• PTSD or DID due to general medical or neurological illness
• History of neurological conditions that may cause significant psychiatric symptomatology (e.g., dementia)
• Any contraindication to MR scans, including claustrophobia, pregnancy, metal implants, etc.
• Current alcohol or substance dependence or abuse (within the last month)
• A history of schizophrenia or other psychotic disorder
• History of head injury or loss of consciousness for longer than 5 min (including concussion)

Where it is running

• McLean Hospital — Belmont, Massachusetts, United States

Full record on ClinicalTrials.gov

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