Nitrous Oxide Versus Intravenous Sedation for Anesthesia

Completed · Not applicable

Conditions studied: Pregnancy Termination in Second Trimester

In brief

This study is a multi-site, double-blinded, randomized, non-inferiority clinical trial of inhaled nitrous oxide with oxygen (N2O/O2) versus intravenous (IV) sedation, with fentanyl and midazolam, for pain management in adult women having a pregnancy termination procedure between 12 and 16 weeks gestational age.

Key facts

Study ID

NCT02755090

Run by

University of New Mexico

People needed

39

Starts

2016-07-01

Expected to finish

2017-05-01

Last updated by the study team

2017-09-15

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• 18 years old or older
• pregnancy termination at gestational age of 12-16 weeks
• able to read and understand either English or Spanish
• able to obtain reliable post-procedure transportation

You may not qualify if…

• contraindications to outpatient pregnancy termination
• contraindications to nitrous oxide use (such as pernicious anemia, current treatment with bleomycin chemotherapy, active upper respiratory illness, or COPD)
• intrauterine fetal demise
• chronic narcotic use
• known adverse reaction to nitrous oxide, Fentanyl, or Versed

Where it is running

• University of Colorado — Denver, Colorado, United States
• University of New Mexico Health Sciences Center — Albuquerque, New Mexico, United States

Full record on ClinicalTrials.gov

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