Cerebral Responses to Insulin Induced Hypoglycemia

Completed · Not applicable

Conditions studied: Type 1 Diabetes, Healthy, Hypoglycemia Unawareness

In brief

This research study is designed to investigate the effect of hypoglycemia (low blood sugar) on blood flow to and biochemistry in the brain.

Key facts

Study ID

NCT02747680

Run by

University of Minnesota

People needed

266

Starts

2004-01-01

Expected to finish

2020-12-01

Last updated by the study team

2021-02-03

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• well controlled type 1 diabetes (hemoglobin A1C <7.5%)
• healthy controls

You may not qualify if…

• History of stroke, seizures, neurosurgical procedures, or arrhythmias
• Use of drugs that can alter GABA (gamma-aminobutyric acid) metabolism (such as benzodiazepines).
• Subjects must also meet requirements for a study in the magnet, which includes weight less than 300 lbs and the absence of metallic substances in their body.

Where it is running

• University of Minnesota — Minneapolis, Minnesota, United States

Full record on ClinicalTrials.gov

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