Alternative Exercise Program to Improve Skeletal Muscle Function and Fatigue in Cancer Survivors

Completed · Not applicable

Conditions studied: Breast Cancer

In brief

Exercise training has beneficial effects in cancer survivors to minimize some of the side effects of cancer and its treatment and improve long-term prognosis, but there are numerous hurdles for individuals diagnosed with, and being treated for, cancer to participate in exercise programs. The goal of this research study is to begin to evaluate whether exercise training via neuromuscular electrical stimulation (NMES) has beneficial effects on skeletal muscle size and function in cancer survivors.

Key facts

Study ID

NCT02739620

Run by

University of Vermont

People needed

22

Starts

2017-10-01

Expected to finish

2019-12-02

Last updated by the study team

2023-04-11

Who can join

Age: 40 and older, up to 70. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• stage I, II or III breast cancer
• receiving neoadjuvant or adjuvant chemotherapy with or without radiation
• a body mass index <35 kg/m2.

You may not qualify if…

• metastatic disease, a prior history of cancer, excluding non-melanoma skin cancer, or prior receipt of chemotherapy
• autoimmune, vascular or neuromuscular disease that could alter skeletal muscle
• prior knee or hip replacement
• contraindications for use of neuromuscular electrical stimulation, including an implanted cardiac defibrillator or pacemaker, lower extremity blood clot or coagulopathy
• pregnancy

Where it is running

• University of Vermont College of Medicine — Burlington, Vermont, United States

Full record on ClinicalTrials.gov

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