Effect of Added Varnum Mouthpiece on Pharyngeal Collapsibility and Sleep Apnea Severity in Mouth Breathers.

Completed · Not applicable

Conditions studied: Obstructive Sleep Apnea

In brief

Test the effect of added a single-use Varnum mouthpiece on pharyngeal collapsibility and obstructive sleep apnea (OSA) severity in patients who identify themselves as mouth breathers. Research indicates that nasal breathing not only may improve sleep apnea but it also increases circulation, blood oxygen, and carbon dioxide levels, slows the breathing rate, and improves overall lung volumes. Thus, the investigators will test whether a single-use Varnum mouthpiece can improve pharyngeal collapsibility and OSA severity in mouth breathers.

Key facts

Study ID

NCT02738255

Run by

David Andrew Wellman

People needed

26

Starts

2016-06-02

Expected to finish

2017-06-15

Last updated by the study team

2022-04-04

Who can join

Age: 21 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Presence of obstructive sleep apnea (AHI>10 events/hr)

You may not qualify if…

• Serious co-morbidities including lung disease, heart disease, renal disease
• Medications affecting respiration or sleep
• Mouth breather subgroup inclusion criteria: self-described mouth breathing habit during sleep.
• non-mouth breathing subgroup inclusion criteria: absence of self-described mouth breathing during sleep

Where it is running

• Sleep Disorders Research Program Brigham and Women's Hospital — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.