Drug Resistance Factors In Healthcare-associated Pneumonia

Completed

Conditions studied: Pneumonia, Critical Illness

In brief

Recently clinical guidelines categorize pneumonia in to three types: community, healthcare-associated, and hospital-acquired. Much of the existing research to describe the epidemiology of pneumonia in critically ill patients comes from single-center studies or from retrospective database analyses, which limit generalizability and lead to over-prescription of broad-spectrum antibacterial agents. This will be a prospective, multicenter epidemiological study to characterize pneumonia epidemiology in critically ill adult patients.

Key facts

Study ID

NCT02736097

Run by

Critical Care Pharmacotherapy Trials Network

People needed

679

Starts

2016-11-01

Expected to finish

2017-02-28

Last updated by the study team

2017-08-01

Who can join

Age: 18 and older, up to 89. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥ 18 years old
• ICU admission
• Empiric or directed anti-infective treatment for pneumonia for ≥ 5 days

You may not qualify if…

• Patient stay in ICU for < 24 hours
• Patient transfer to the ICU from a hospital floor following prescription for anti-infective therapy in the previous 24 hours of ICU admission
• Diagnosis of cystic fibrosis or bronchiectasis
• Fungal pneumonia

Where it is running

• University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
• Hartford Healthcare — Hartford, Connecticut, United States
• University of Florida - Jacksonville Hospital — Jacksonville, Florida, United States
• Cleveland Clinic - Florida — Weston, Florida, United States
• Memorial University Medical Center — Savannah, Georgia, United States
• University of Chicago Medical Center — Chicago, Illinois, United States
• Rush University Medical Center — Chicago, Illinois, United States
• Roudebush - Indianapolis Veterans Administration Hospital — Indianapolis, Indiana, United States
• University of Kentucky Healthcare - Chandler Medical Center — Lexington, Kentucky, United States
• Ochsner Clinic Foundation — New Orleans, Louisiana, United States
• Brigham and Women's Hospital — Boston, Massachusetts, United States
• Massachusetts General Hospital — Boston, Massachusetts, United States
• Detroit Medical Center — Detroit, Michigan, United States
• Spectrum Health — Grand Rapids, Michigan, United States
• Beaumont Health System — Royal Oak, Michigan, United States
• University of Minnesota - Fairview Health Services — Minneapolis, Minnesota, United States
• Northeast Regional Medical Center — Kirksville, Missouri, United States
• Lakes Regional General Healthcare — Laconia, New Hampshire, United States
• Hackensack University Medical Center — Hackensack, New Jersey, United States
• University of Rochester Medical Center — Rochester, New York, United States
• Mercy Medical Center — Canton, Ohio, United States
• Cleveland Clinic - Cleveland — Cleveland, Ohio, United States
• Allegheny Health Network — Pittsburgh, Pennsylvania, United States
• Roper St. Francis Healthcare — Charleston, South Carolina, United States
• Vanderbilt University Medical Center — Nashville, Tennessee, United States

Full record on ClinicalTrials.gov

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