Effect of Meibomian Gland Probing on Ocular Surface in Ocular Rosacea

Withdrawn before enrolling · Not applicable

Conditions studied: Meibomian Gland Dysfunction

In brief

Meibomian glands (MG) are modified sebaceous glands associated with the tarsus (collagenous structural component) of the upper and lower eyelids. Meibomian glands produce lipid-based secretions which are an integral and stabilizing part of the tear film. In blepharitis and ocular rosacea (two known causes of obstructive meibomian gland dysfunction (o-MGD), inflammation of the lid margins causes blockage of the meibomian gland orifices, changes in glandular secretions, and dropout of the glands themselves. This limits the production, secretion, and quality of meibum. With less oil in the tear film, the aqueous portion of tears is not stable and evaporates quickly which leads to dry eye.

Key facts

Study ID

NCT02735681

Run by

University of Arkansas

People needed

0

Starts

2017-02-01

Expected to finish

2018-03-28

Last updated by the study team

2018-04-26

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosed Ocular Rosacea +/- Facial Rosacea

You may not qualify if…

• Prior meibomian gland probing
• Prior treatment with Lipiflow
• Cicatricial Disease
• Sjogren's Syndrome
• Prior radiation therapy to face / head
• Allergy to lissamine green and fluorescein

Where it is running

• Jones Eye Institute, UAMS — Little Rock, Arkansas, United States

Full record on ClinicalTrials.gov

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