Dendritic Cell/Myeloma Fusion Vaccine for Multiple Myeloma (BMT CTN 1401)
Completed · Phase 2
Conditions studied: Multiple Myeloma
In brief
The study is designed as a Phase II, multicenter trial of vaccination with Dendritic cell/myeloma fusions with granulocyte macrophage colony-stimulating factor (GM-CSF) adjuvant plus lenalidomide maintenance therapy versus maintenance therapy alone or with GM-CSF following autologous transplant as part of upfront treatment of multiple myeloma (MM). It is hypothesized that the dendritic cell myeloma vaccine will result in improved response in patients with multiple myeloma after autologous Hematopoietic Cell Transplant (HCT).
Key facts
- Study ID
- NCT02728102
- Run by
- National Heart, Lung, and Blood Institute (NHLBI)
- People needed
- 203
- Starts
- 2016-07-01
- Expected to finish
- 2022-12-09
- Last updated by the study team
- 2024-05-07
Who can join
Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.
Where it is running
- University of California, San Francisco — San Francisco, California, United States
- Emory University — Atlanta, Georgia, United States
- University of Maryland/Greenebaum Cancer Center — Baltimore, Maryland, United States
- Beth Israel Deaconess Medical Center/Dana Farber Cancer Institute — Boston, Massachusetts, United States
- University of Minnesota — Minneapolis, Minnesota, United States
- University of Nebraska Medical Center — Omaha, Nebraska, United States
- Roswell Park Cancer Institute — Buffalo, New York, United States
- Mount Sinai Medical Center — New York, New York, United States
- Memorial Sloan-Kettering Cancer Center — New York, New York, United States
- University Hospitals of Cleveland/Case Western — Cleveland, Ohio, United States
- Ohio State University/Arthur G. James Cancer Hospital — Columbus, Ohio, United States
- University of Texas/MD Anderson Cancer Center — Houston, Texas, United States
- Fred Hutchinson Cancer Research Center — Seattle, Washington, United States
- University of Wisconsin Hospital & Clinics — Madison, Wisconsin, United States
- Medical College of Wisconsin — Milwaukee, Wisconsin, United States
Full record on ClinicalTrials.gov
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