Measuring Cortisol Levels in Persons With Parkinson's (PD)

Completed

Conditions studied: Parkinson Disease, Huntington Disease

In brief

The objective of this study is to evaluate the cortisol awakening response with persons with Parkinsons Disease (PD), Huntingtons Disease (HD), and controls. These data are desired so experience can be gained with measuring stress levels subjectively and objectively in persons with PD, HD, and controls.

Key facts

Study ID

NCT02727270

Run by

Oregon Health and Science University

People needed

131

Starts

2016-06-01

Expected to finish

2023-11-16

Last updated by the study team

2023-12-22

Who can join

Age: 18 and older, up to 99. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Group (3) Inclusion:
• No significant neurological disorder
• PSS score of greater than or equal to 13.
• Group (5) Inclusion:
• HD diagnosis or HD gene carrier
• a Perceived Stress Scale (PSS) score higher than or equal to 13.
• Group (6) Inclusion:
• HD diagnosis or HD gene carrier
• PSS score lower than 13
• Group (7) Inclusion:
• PD diagnosis
• Prior completion of the study.

You may not qualify if…

• The use of medications known to effect cortisol levels (estrogen, synthetic glucocorticoids, androgens, phenytoin, spironolactone, prednisone, prednisolone, and hydrocortisone).

Where it is running

• Oregon Health & Science Universtiy — Portland, Oregon, United States
• VA Portland Health Care System — Portland, Oregon, United States

Full record on ClinicalTrials.gov

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