Effect of Pumpkin Seed Oil or Pumpkin Seeds on Blood Pressure and Menopausal Symptoms in Postmenopausal Women

Completed · Not applicable

Conditions studied: Hypertension, Dyslipidemia

In brief

The purpose of this randomized control trial is to compare the effect of pumpkin seed oil 2g/day with pumpkin seeds given as a dose of 1½ teaspoons/ 4.1 grams a day to provide 2g of lipid (equivalent to 2 grams of oil) on BP (systolic and diastolic), endothelial function, serum lipids, C-reactive protein (CRP) concentrations, and menopausal symptoms in postmenopausal women.

Key facts

Study ID

NCT02727036

Run by

Texas Woman's University

People needed

27

Starts

2015-08-01

Expected to finish

2017-11-10

Last updated by the study team

2018-05-03

Who can join

Age: any. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Non-hypertensive with blood pressure less than140/90 mmHg
• Post menopausal women or had a bilateral oophorectomy

You may not qualify if…

• Hypotensive women with BP <90/60
• Taking medications to manage blood pressure and blood lipids
• Taking estrogen supplements or on hormone replacement therapy
• Taking pumpkin seed oil supplements
• Consuming pumpkin seeds more than ¼ cup a month
• Diagnosed with depression and taking antidepressants

Where it is running

• Texas Woman's University — Houston, Texas, United States

Full record on ClinicalTrials.gov

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