Vitamin D and Prostate Cancer: A Clinical Study Enrolling Subjects Undergoing Prostatectomy

Completed · Phase 2 · Has a placebo group

Conditions studied: Prostate Cancer

In brief

The study population will be 80 adult men who have been diagnosed with prostate cancer who are scheduled to have their prostate surgically removed at either the Medical University of South Carolina (MUSC) or the Ralph H. Johnson VAMC, both located in Charleston, SC. The men will be randomized into two groups: one group will take vitamin D3 supplementation and the other will take a placebo. Blood levels of vitamin D3 will be obtained at the beginning of the study and again after two months, just prior to the surgical procedure (prostatectomy). Prostate tissue will be obtained from the surgical procedure and studied for the effect of vitamin D on the prostate cancer cells.

Key facts

Study ID

NCT02726113

Run by

Medical University of South Carolina

People needed

50

Starts

2011-10-01

Expected to finish

2015-12-01

Last updated by the study team

2019-12-03

Who can join

Age: 19 and older, up to 90. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of prostate cancer (by prostate biopsy)
• Scheduled to undergo a prostatectomy
• Ability to give his own consent to participate in the study

You may not qualify if…

• Serum 25(OH)D level less than 8ng/ml or greater than 50 ng/ml
• Vitamin D3 supplementation greater than or equal to 1000 IU daily

Where it is running

• Ralph H. Johnson VA Medical Center — Charleston, South Carolina, United States
• MUSC (Medical University of South Carolina) — Charleston, South Carolina, United States

Full record on ClinicalTrials.gov

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