Comparative Study of Superficial Cervical Plexus Block and Nerve of Arnold Block and Incidence of PONV for Inner Ear Surgery

Stopped early · Phase 4

Conditions studied: Anesthesia, Pediatrics, Surgery

In brief

The investigators would like to compare the therapeutic and cost effectiveness of established therapies for postoperative nausea and vomiting to regional nerve blocks of the head and neck area an intervention known for analgesia but for which the antiemetic effects hasn't been entirely explored. The rational is based on the knowledge of the anatomical innervation of the inner ear and the role of the parasympathetic nervous system in the emetic act. A lot of focus has been given on its counterpart the sympathetic nervous system and its role in painful conditions. The investigators believe that the nerve blockade of the parasympathetic innervation can have some beneficial effect in the post-surgical patient.

Key facts

Study ID

NCT02724033

Run by

Indiana University

People needed

37

Starts

2014-05-01

Expected to finish

2018-09-01

Last updated by the study team

2020-06-16

Who can join

Age: 1 and older, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patient Age 1-18 yo
• Scheduled to have cochlear implantation, Tympanomastoidectomy, inner ear surgery
• Past history of PONV susceptibility

You may not qualify if…

• Patient/ Parents refusal
• Infection at the site of local anesthetic injection
• Known coagulopathy
• Existing VP shunt
• Severe mental disability
• Any known allergic to dexamethasone (Decadron) and/or ondansetron ( Zofran)

Where it is running

• Riley Hospital for Children — Indianapolis, Indiana, United States

Full record on ClinicalTrials.gov

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