Appetite Regulation in Older-Aged Obese Individuals
Completed · Not applicable
Conditions studied: Obesity, Aging
In brief
This study plans to learn more about how age and weight impact appetite and food intake. Specifically, this study is being done to see whether age and obesity impact appetite and the brain's response to food. In this study the investigators will be evaluating how participants brains respond to food images as well as your food-related behaviors and hormones. The investigators will be comparing older individuals aged 65 to 85 years who are normal weight compared to those who are obese. The Investigators will then compare older aged individuals to younger adults aged 21 to 45 years.
Key facts
- Study ID
- NCT02721303
- Run by
- University of Colorado, Denver
- People needed
- 37
- Starts
- 2016-05-01
- Expected to finish
- 2020-10-31
- Last updated by the study team
- 2021-01-06
Who can join
Age: 21 and older, up to 85. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Older aged adults (O): 65-85
- Younger adults (Y): 21-45
- Obese (Ob): body mass index (BMI) 30-40
- Normal Weight (NW): BMI 18-25
You may not qualify if…
- Pregnancy;
- Advanced organ failure;
- Active cancer diagnosis;
- Uncontrolled hypertension or metabolic disorder;
- Cognitive impairment or psychiatric disease limiting ability to comply;
- Presently in an exercise or diet program;
- Recent weight loss of >5 lbs in past 6 mo.;
- Bariatric surgery;
- Use of any weight loss drugs;
- Use of any medication known to significantly affect appetite (anti-depressants are allowable);
- Present tobacco use;
- Use/abuse of substances of abuse including any marijuana use by history;
- Any contraindication to MRI;
- Claustrophobia;
- Body weight >300 lbs; and
- Inability to fit in MRI scanner.
Where it is running
- Univeristy of Colorado — Aurora, Colorado, United States
Full record on ClinicalTrials.gov
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