Exercise in Multiple Sclerosis
Stopped early · Not applicable
Conditions studied: Multiple Sclerosis
In brief
Exercise therapy in MS patients has proven benefits on mobility, mood, motor function and quality of life. While the beneficial effects of exercise on cardiovascular and musculoskeletal function are well known, there has recently been increased focus on the positive effects of exercise on brain structure and function. The goal of this study is to determine whether exercise can promote beneficial changes in brain function in MS patients.
Key facts
- Study ID
- NCT02716701
- Run by
- University of Minnesota
- People needed
- 40
- Starts
- 2016-01-01
- Expected to finish
- 2020-08-13
- Last updated by the study team
- 2020-08-25
Who can join
Age: 18 and older, up to 100. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Male or female patients with a confirmed diagnosis of MS by revised McDonald criteria
- Age ≥ 18 years
- Expanded Disability Status Scale (EDSS) 0-6.0, inclusive.
- Able to understand the consent process, and the use of the wristband activity tracker.
- Sedentary by self-report (answers no to the question: "Do you exercise regularly?"
- Willing to make sincere effort to comply with the study objective of increasing their physical activity as much as possible (with goal of at least 100% increase) and to maintain that increased activity level for six months (if randomized to the exercise group).
You may not qualify if…
- Current serious medical condition which would likely limit subject's ability to achieve sustained increase in physical activity, or put them at risk for doing so in the investigators' opinion (e.g. significant cardiovascular or respiratory disease, cancer, cancer, orthopedic disease, etc)
- Subjects that have a central nervous system disorder (in addition to MS) that is not considered secondary to MS
- Subjects that have implanted metal, pacemaker, etc. that may interfere with the MEG/MRI scan or who are otherwise unable to complete the MEG/MRI scan procedure without sedation (e.g. due to claustrophobia, obesity)
- weight > 300 pounds
Where it is running
- VA Medical Center — Minneapolis, Minnesota, United States
Full record on ClinicalTrials.gov
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