Benefits of Physical Exercise in Schizophrenia

Completed · Not applicable

Conditions studied: Schizophrenia

In brief

Impairments in social integration, characterized by low marriage rates, few friendships, and a high frequency of living alone, affect the vast majority of Veterans with schizophrenia. The primary aim of this proposal is to test the efficacy of a novel rehabilitation treatment approach, engaging in physical exercise, at improving two determinants of social integration which are impaired in schizophrenia: cognition and affect.

Key facts

Study ID

NCT02716584

Run by

VA Office of Research and Development

People needed

53

Starts

2016-09-01

Expected to finish

2018-07-12

Last updated by the study team

2019-09-19

Who can join

Age: 40 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnostic and Statistical Manual (DSM) - 5 diagnosis of schizophrenia or schizoaffective disorder;
• age 40-65;
• screened for physical health risks (i.e., no serious heart condition, dizziness, bone or joint problems posing safety concerns, ambulatory limitations);
• clinically stable (e.g., no inpatient hospitalizations for 3 months prior to enrollment; no change in type of antipsychotic medication in the past 4 weeks)

You may not qualify if…

• evidence of alcohol or substance use disorder (moderate or greater severity) per DSM-5 criteria in the past 3 months;
• clinically significant neurological disease as determined by medical history (e.g., seizure disorder);
• history of serious head injury with loss of consciousness >1 hour;
• participation in an exercise program within past 6 months;
• not able to understand spoken and written English sufficiently to comprehend consent procedures.

Where it is running

• VA Greater Los Angeles Healthcare System, West Los Angeles, CA — West Los Angeles, California, United States

Full record on ClinicalTrials.gov

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