Water And Saline Head-to-head In The Blinded Evaluation Study Trial

Completed · Not applicable

Conditions studied: Acute Appendicitis, Abscess

In brief

Patients who are diagnosed with acute appendicitis consented and then randomized into two arms of the trial. In one arm, patients receive irrigation of the abdomen during surgery with normal saline, or salt water. In the other arm, patients receive irrigation of the abdomen during surgery with sterile water. Sometimes patients receive no irrigation if none is determined to be needed at the time of operation by the surgeon. We then followed patients after surgery for 30 days. The hypothesis of this study was that the use of sterile water as irrigation fluid during surgery in patients who have acute appendicitis will decrease the chance of a post-operative abscess or infection.

Key facts

Study ID

NCT02714023

Run by

University of Missouri-Columbia

People needed

241

Starts

2012-10-10

Expected to finish

2017-11-29

Last updated by the study team

2018-10-15

Who can join

Age: 6 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• All patients, age 6 and older, who present for an emergent or interval appendectomy to any one of the participating surgeons, meet the inclusion criteria for the study. Assent from all minors (under age 18) was obtained.

You may not qualify if…

• Pregnant patients, patients with mental handicap, Veterans, patients under 6 years old

Where it is running

• University of Missouri — Columbia, Missouri, United States

Full record on ClinicalTrials.gov

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