Anti-vasculaR Endothelial Growth Factor plUs Anti-angiopoietin 2 in Fixed comBination therapY: Evaluation for the Treatment of Diabetic Macular Edema

Completed · Phase 2

Conditions studied: Diabetic Macular Edema

In brief

The primary objective of the study was to compare the efficacy of intravitreal (IVT)-administered REGN910-3 compared to intravitreal aflibercept injection (IAI) in improving best corrected visual acuity (BCVA) in participants with diabetic macular edema (DME).

Key facts

Study ID

NCT02712008

Run by

Regeneron Pharmaceuticals

People needed

302

Starts

2016-03-02

Expected to finish

2017-07-10

Last updated by the study team

2018-10-03

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Study site — Tucson, Arizona, United States
• Study site — Arcadia, California, United States
• Study site — Beverly Hills, California, United States
• Study site — Mountain View, California, United States
• Study site — Oceanside, California, United States
• Study site — Palm Desert, California, United States
• Study site — Colorado Springs, Colorado, United States
• Study site — New London, Connecticut, United States
• Study site — Lakeland, Florida, United States
• Study site — Tampa, Florida, United States
• Study site — Winter Haven, Florida, United States
• Study site — Augusta, Georgia, United States
• Study site — Decatur, Georgia, United States
• Study site — ‘Aiea, Hawaii, United States
• Study site — Chicago, Illinois, United States
• Study site — New Albany, Indiana, United States
• Study site — Shawnee Mission, Kansas, United States
• Study site — Lexington, Kentucky, United States
• Study site — Portland, Maine, United States
• Study site — Baltimore, Maryland, United States
• Study site — Rockville, Maryland, United States
• Study site — Boston, Massachusetts, United States
• Study site — Grand Rapids, Michigan, United States
• Study site — Jackson, Michigan, United States
• Study site — Mesa, Arizona, United States

Full record on ClinicalTrials.gov

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