Clinical Outcomes of Buffered 1% Lidocaine vs. Non-buffered 2% Lidocaine

Completed · Not applicable

Conditions studied: Anesthesia

In brief

Anecdotal data suggest that the buffered form of the local anesthetic is more potent at equal dosages, and a lower dosage of the drug might be used with an effect equal to higher dosage not buffered. Clinical data are needed to confirm these anecdotal data. No data exist comparing buffered local anesthetics at lower drug concentrations to current dosages commonly used in dental and oral surgical procedures

Key facts

Study ID

NCT02708433

Run by

University of North Carolina, Chapel Hill

People needed

23

Starts

2016-03-01

Expected to finish

2017-09-01

Last updated by the study team

2018-09-04

Who can join

Age: 18 and older, up to 30. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 18-30 years, ASA I

You may not qualify if…

• Allergy to lidocaine class of anesthetic drugs Local anesthetic drug use in past week Current symptoms teeth or oral mucosa

Where it is running

• UNC School of Dentistry — Chapel Hill, North Carolina, United States

Full record on ClinicalTrials.gov

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