Single Dose Preoperative Gabapentin Use in Minimally Invasive Hysterectomy for Acute Pain Management

Completed · Phase 4

Conditions studied: Pain, Postoperative

In brief

The purpose of the investigators' study is to assess the efficacy of a single dose of preoperative gabapentin within an enhanced recovery after surgery protocol in acute postoperative pain reduction for women undergoing a minimally invasive hysterectomy. Participants who consent to participate will be randomized to either a control group without gabapentin or to a study arm and receive gabapentin 600 mg prior to their planned surgery. The investigators will collect data on postoperative narcotic use, subjective pain as rated by a numeric pain scale, in addition to any adverse effects of single dose gabapentin use.

Key facts

Study ID

NCT02703259

Run by

Christiana Care Health Services

People needed

137

Starts

2016-06-01

Expected to finish

2017-07-01

Last updated by the study team

2020-05-20

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• undergoing a minimally invasive hysterectomy with surgeons operating within the Christiana Care Health System at the Newark location only.
• at least 18 years of age
• able to swallow tablets or capsules

You may not qualify if…

• liver failure
• renal failure
• prior gastric bypass
• gastroparesis
• recent or current regular gabapentin use
• hypersensitivity to gabapentin, acetominophen, or celecoxib
• procedure is converted to laparotomy for any indication. (Mini-laparotomy for specimen removal alone will not be excluded.)

Where it is running

• Christiana Care Health System — Newark, Delaware, United States

Full record on ClinicalTrials.gov

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