A Comprehensive Care Plan for Pediatric Patients With Vaso-Occlusive Crises

Stopped early · Not applicable

Conditions studied: Sickle Cell Disease, Sickle Cell Crisis, Vaso-Occlusive Crises

In brief

Sickle cell disease (SCD) is the most common inherited blood disorder affecting 80,000 to 90,000 individuals in the United States.\[10\] There are 13,000 hospital admissions for a sickle cell crises, costing $448 million dollars annually.\[10\] In our hospital, the sickle cell population is known to have some of the longest length of stays. Between October 2014 and September 2015, there were 89 admissions for a vaso-occlusive crisis with an average length of stay of 6 days and 12 admissions greater than 10 days and 5 admissions greater than 20 days. We propose to evaluate the feasibility of the new CPP in a pilot randomized control trial to determine if pain and length of stay can be reduced in patients with sickle cell disease. We also propose to evaluate a sleep regimen to determine if this can reduce the hospital stay and help with pain. We hypothesize increased physical activity and proper sleep, as implemented in the CPP, are correlated with decreased hospital length of stay and decreased pain. Additionally, we believe that creating a standardized nighttime environment at the hospital will help the children stay in their circadian rhythm thus promoting improved sleep and a more effective inpatient disease management.

Key facts

Study ID

NCT02698761

Run by

Valley Anesthesiology Consultants

People needed

3

Starts

2016-04-01

Expected to finish

2018-03-01

Last updated by the study team

2018-05-03

Who can join

Age: 12 and older, up to 18. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Children between 12 and 18 years of age who are admitted to the hospital for an acute vaso-occlusive crisis
• Patients must require a demand PCA and able to tolerate oral pain medications

You may not qualify if…

• - Requires a continuous PCA
• Unwilling to be compliant with the assigned arm of study (e.g. Non-compliance with sleep or visiting regimen, or questionnaires)
• Non-English speaking child or parent (questionnaires not available/validated in another language)

Where it is running

• Phoenix Children's Hospital — Phoenix, Arizona, United States

Full record on ClinicalTrials.gov

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