Assessment of Global Myocardial Perfusion Reserve Using Coronary Sinus Flow Measurements

Completed

Conditions studied: Coronary Artery Disease

In brief

The aim of this study is to assess whether myocardial perfusion reserve, measured during routine clinically ordered regadenoson stress cardiac magnetic resonance (CMR) has prognostic value in predicting adverse cardiovascular events. Myocardial perfusion reserve will be measured with CMR by assessing blood flow through the coronary-sinus - the primary vein in the heart.

Key facts

Study ID

NCT02697877

Run by

University of Illinois at Chicago

People needed

183

Starts

2016-02-01

Expected to finish

2018-07-01

Last updated by the study team

2019-10-24

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥18
• Male or Female
• Referred for clinical cardiac magnetic resonance stress testing (with Regadenoson) at the University of Illinois Hospital \& Health Sciences System by their healthcare provider as part of their routine clinical care for known or suspected coronary artery disease.

You may not qualify if…

• Presence of metallic implants contraindicated with cardiac magnetic resonance (e.g. implantable cardiac defibrillator, pacemaker)
• Glomerular Filtration Rate (GFR) <30ml/min
• High degree atrio-ventricular block
• Hypersensitivity to Regadenoson
• Severe active wheezing from asthma
• Severe claustrophobia

Where it is running

• 1740 W Taylor Street, 2nd Floor, Cardiac Imaging — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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