Retention of Potassium From Potatoes and Potassium Gluconate, and the Effect on Blood Pressure.
Status unconfirmed · Phase 1/Phase 2
Conditions studied: Hypertensive Disease
In brief
This study is designed to compare the effect of different dietary potassium sources on uptake and retention of potassium, as well as to determine the effect of potassium intake on blood pressure and acid-base balance. The study will compare three different sources of potassium given as a supplement, potatoes or French fries.
Key facts
- Study ID
- NCT02697708
- Run by
- Purdue University
- People needed
- 40
- Starts
- 2016-04-27
- Expected to finish
- 2018-12-31
- Last updated by the study team
- 2018-05-09
Who can join
Age: 21 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Age 21 and above
- Subjects able to adhere to the visit schedule and protocol requirements and be available to complete the study.
- Pre-hypertensive, (SBP: 120-159mmHg).
You may not qualify if…
- Subjects taking more than one medication to treat hypertension
- Subject is taking medication to treat hypotension, or medication known to affect electrolyte metabolism or contain high levels of potassium or sodium, smoke cigarettes, use illegal drugs, or excessive alcohol intake.
- Current use systemic corticosteroids, androgens, phenytoin, erythromycin, thyroid hormones, lipid-lowering medication.
- Subjects who have hypertension (SBP > 160 mmHg), hypotension (SBP < 120mmHg) or diseases known to affect potassium metabolism (kidney disease or malabsorption disorders). History of myocardial infarction, diabetes mellitus, renal disease, gastrointestinal disease, pancreatitis, cholestatic liver disease, cancer.
- Subjects who are pregnant.
- Allergy or intolerance of intervention foods.
- Unwillingness to refrain from dietary supplements.
- Weight loss > 3kg in the past 2 months.
- Subjects with liver and/or lipid abnormalities (elevated alanine amino transferase (ALT) and aspartate amino transferase (AST), dyslipidemia).
Where it is running
- Department of Nutrition Science Purdue University — West Lafayette, Indiana, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.