Targeted Genomic Analysis of Blood and Tissue Samples From Patients With Cancer

Recruiting now

Conditions studied: Malignant Neoplasm

In brief

This research trial studies the use of targeted genomic analysis of blood and tissue samples from patients with cancer. Genomic sequencing is a laboratory method that is used to determine the entire genetic makeup of a specific organism or cell type. Genomic sequencing can be used to find changes in areas of the genome that may be important in the development of cancer. It may also help doctors improve ways to diagnose and treat patients with rare cancers with poor prognosis or lack of effective therapy.

Key facts

Study ID

NCT02688517

Run by

Rutgers, The State University of New Jersey

People needed

1100

Starts

2013-02-01

Expected to finish

2030-05-01

Last updated by the study team

2026-04-17

Who can join

Age: 1 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Karnofsky/Lansky performance score >= 30
• A signed written informed consent
• Evaluation in surgical/medical/radiation oncology/radiology clinic, with a history of biopsy-confirmed diagnosis of cancer of rare histology and/or poor prognosis with standard therapy; priority will be given to rare cancers with poor prognosis and lack of effective standard therapy; study principal investigator (PI) or designee will review and approve each case before enrollment
• Paraffin blocks of the patient's tumor tissue are available and accessible for analysis

You may not qualify if…

• Karnofsky/Lansky performance score < 30
• Life expectancy < 3 months

Where it is running

• RWJBarnabas Health - Jersey City Medical Center, Jersey City — Jersey City, New Jersey, United States (enrolling)
• Rutgers Cancer Institute of New Jersey — New Brunswick, New Jersey, United States (enrolling)
• Southern Ocean County Medical Center — Manahawkin, New Jersey, United States
• Morristown Medical Center — Morristown, New Jersey, United States
• Jersey Shore Medical Center — Neptune City, New Jersey, United States
• Riverview Medical Center/Booker Cancer Center — Red Bank, New Jersey, United States
• Riverview Medical Center — Red Bank, New Jersey, United States
• Overlook Hospital — Summit, New Jersey, United States
• Ocean Medical Center — Brick, New Jersey, United States
• University of Wisconsin Hospital and Clinics — Madison, Wisconsin, United States
• Bayshore Community Hospital — Holmdel, New Jersey, United States

Full record on ClinicalTrials.gov

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