Light-deprivation Utilized to Mitigate Amblyopia

Status unconfirmed · Not applicable

Conditions studied: Amblyopia

In brief

Amblyopia is an impairment in spatial vision caused by asymmetry in the quality of visual input across the two eyes during childhood. It is difficult to treat in adulthood because the visual system becomes less "plastic" (able to learn) with age. The purpose of this study is to determine whether five to ten days of visual deprivation--living in complete darkness--can enhance plasticity in the visual cortex and thereby facilitate the learning that is needed to recover visual function in amblyopic adults.

Key facts

Study ID

NCT02685423

Run by

State University of New York College of Optometry

People needed

8

Starts

2016-12-01

Expected to finish

2019-12-31

Last updated by the study team

2019-08-29

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Adults age 18 or older
• Moderate (20/30 to 20/80) to severe (20/100 to 20/400) amblyopia with a visual acuity of 20/25 or better in the fellow eye
• Must live in or be commutable to the New York Metropolitan area

You may not qualify if…

• individuals with study-relevant phobias, anxiety disorders or other mental health disorders will be excluded, as will people taking anti-depressant or anti-anxiety drugs
• Must pass all stages of application process:
• Review of full application
• Phone interview
• Telephone interview of two personal references
• On-site eligibility screening evaluation
• On-site complete ophthalmic evaluation
• Criminal background check
• On-site personal interview
• Psychological exam
• Physical exam

Where it is running

• SUNY College of Optometry - Clinical Vision Research Center — New York, New York, United States

Full record on ClinicalTrials.gov

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