Optimizing Chronic Pain Treatment With Enhanced Neuroplastic Responsiveness
Completed · Not applicable
Conditions studied: Pain, Osteoarthritis
In brief
The purpose of the study is to identify non-invasive strategies that will optimize the neurobiological environment and improve learning and memory in the treatment of chronic pain. The overall aims of the current proposal are to determine if food restriction and/or glucose administration in conjunction with a relaxation/guided imagery exercise will result in neurophysiological changes and functional improvements compared to the relaxation/guided imagery exercise alone.
Key facts
- Study ID
- NCT02681081
- Run by
- University of Florida
- People needed
- 26
- Starts
- 2016-02-01
- Expected to finish
- 2019-07-12
- Last updated by the study team
- 2019-07-15
Who can join
Age: 50 and older, up to 85. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Adults with chronic knee pain with or/at risk of knee osteoarthritis
You may not qualify if…
- Concurrent medical condition that could confound outcome measures or limit the ability to participate completely in the protocol including: neurological conditions (Parkinson's disease, multiple sclerosis, and/or seizures)
- History of a head injury or stroke
- Diabetes or taking medications to control blood sugar
- Mental health issues resulting in hospitalization or outpatient treatment in the past year, and/or psychotropic medication use
- Current issue or history of treatment for alcohol or other substance abuse
- Cognitive function < or = 22 on the Mini-Mental Status Exam
- Pregnancy
- A baseline fasting blood sugar (plasma glucose > 7mmol/L) or persisting blood pressure >150/95.
- Heart condition such as a prior heart attack, heart surgery (including a stent), frequent chest pain or heart failure
- Inability to complete the EEG portion of the study
Where it is running
- Institute of Aging — Gainesville, Florida, United States
Full record on ClinicalTrials.gov
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