Vitamin D Levels Following Topical Application of Vitamin D Ointment
Completed · Phase 1
Conditions studied: Vitamin D Deficiency
In brief
This is a pre-post open label trial to assess the change in Vitamin D blood levels following treatment with three doses of topical Vitamin D3 in subjects with existing Vitamin D deficiency.
Key facts
- Study ID
- NCT02676674
- Run by
- University of Minnesota
- People needed
- 10
- Starts
- 2016-03-01
- Expected to finish
- 2017-06-15
- Last updated by the study team
- 2019-11-01
Who can join
Age: 18 and older, up to 85. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Known vitamin D deficiency based on blood work obtained prior to study consent defined as serum 25-hydroxyvitamin D less than or equal to 20 ng/mL within 30 days prior to study entry.
- Adult, age 18 to 85 years, male or female
- If on oral vitamin D therapy, have been on a stable dose for the previous 90 days.
You may not qualify if…
- History of chronic liver disease with elevated liver function tests, chronic kidney disease (stage 3 or greater, eGFR <60 mL/min), uncontrolled thyroid disease (elevated thyroid function tests), primary or secondary hyperparathyroidism, hypercalcemia, or multiple endocrine neoplasia.
- Hypercalcemia defined as either elevated corrected serum calcium >10.2 mg/dL) measured within 3 months prior to study.
- estimated glomerular filtration rate (eGFR) <60 mL/min within 3 months prior to study.
- Active cancers
- Women who are pregnant or breastfeeding.
- Individuals who are unable to give informed consent
- Individuals with psoriasis, active eczema or other skin disease, or who are currently receiving treatments or medications for skin disease.
- Individuals who do not agree to refrain from using tanning beds for the duration of the study.
- Individuals who do not agree to avoid submerging the ointment site in water for 8 hours after ointment application.
Where it is running
- University of Minnesota Physicians - Phalen Village Clinic — Saint Paul, Minnesota, United States
Full record on ClinicalTrials.gov
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