Study Comparing Fish Oil and Krill Oil
Stopped early · Not applicable
Conditions studied: Inflammation, Dyslipidemia
In brief
Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are omega-3 fatty acids found in fish oil and in krill oil. The purpose of this study is to compare the effects of the recommended dose of a fish oil supplement (Omax3 4:1 EPA:DHA; recommended daily dose 1650 mg - totaling 1500 mg EPA+DHA) and a krill oil supplement (MegaRed; recommended daily dose 300 mg - totaling 74 mg EPA+DHA) on omega-3 index, plasma biomarkers of inflammation and inflammatory cell activation, and plasma lipid levels in subjects with metabolic syndrome.
Key facts
- Study ID
- NCT02670356
- Run by
- Tufts University
- People needed
- 2
- Starts
- 2015-10-01
- Expected to finish
- 2016-07-01
- Last updated by the study team
- 2017-04-26
Who can join
Age: 50 and older, up to 75. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- fasting plasma triglyceride levels between 150 and 500 mg/dL
- C-reactive protein (CRP) levels ≥2 µg/mL
- at least one of the following criteria for the definition of metabolic syndrome: abdominal obesity (waist circumference >40 inches in men and >35 inches in women), hypertension (blood pressure ≥130/≥85 mmHg or use of anti-hypertensive medications), and fasting glucose ≥110 mg/dL.
You may not qualify if…
- high-fish diets (>2 fish meals/week)
- taking fish oil supplements or supplements containing EPA or DHA
- regular use of anti-inflammatory medications
- Above normal coagulation time or use of anticoagulant medications
- allergy to fish, fish oil, or shellfish
- uncontrolled thyroid dysfunction
- insulin-dependent type 2 diabetes mellitus
- kidney or liver disease
- smoking
- drinking more than 7 alcoholic drinks/week
- use of lipid-lowering medications or medications known to alter lipoprotein metabolism
Where it is running
- Jean Mayer Human Nutrition Research Center on Aging at Tufts University — Boston, Massachusetts, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.