Use of 3-D Blood Pool Scintigraphy to Guide Left Ventricular Pacing Lead Placement in Patients Requiring Cardiac Resynchronization Therapy

Stopped early · Not applicable

Conditions studied: Heart Failure, Left Ventricular Dysfunction, Cardiac Resynchronization Therapy

In brief

The purpose of this study is to determine whether multiple gated acquisition (MUGA) guided lead placement improves clinical outcomes for patients needing cardiac resynchronization therapy (CRT) compared to traditional posterolateral left ventricular lead placement.

Key facts

Study ID: NCT02669290
Run by: University of California, San Francisco
People needed: 60
Starts: 2007-01-01
Expected to finish: 2018-01-01
Last updated by the study team: 2020-01-13

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Male or female, 18 years or older
Must have an approved indication for CRT implantation
Must have ischemic or nonischemic dilated cardiomyopathy
Must have symptomatic HF with a New York Association (NYHA) Classification of III or IV
Must be on optimal pharmacological therapy (this should include at the minimum, ACE inhibitor and beta-blocker therapy as tolerated.
Must have left ventricular ejection fraction (LVEF) of ≤35%
Must have ventricular conduction delay manifested as a QRS duration of >120msec
Must be able to provide informed consent for study participation and be willing to comply with follow-up tests and scheduled visits

You may not qualify if…

HF diagnosis for less than 3 months
Physical limitations to ambulation
Life expectancy of less than six months
Pregnant or planning for pregnancy in the next 6 months (must have a negative pregnancy test 7 days prior to enrollment)

Where it is running

University of California, San Francisco — San Francisco, California, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.