Topical (Intra-Articular) Tranexamic Acid and Transfusion Rates Following Hip Hemiarthroplasty

Completed · Phase 4 · Has a placebo group

Conditions studied: Femoral Neck Fractures

In brief

This study is a double-blinded placebo-controlled clinical trial evaluating the efficacy of 1 gram of topically applied tranexamic acid vs. saline placebo for the reduction of transfusion following hip hemiarthroplasty surgery.

Key facts

Study ID

NCT02664909

Run by

UConn Health

People needed

36

Starts

2016-01-01

Expected to finish

2019-06-30

Last updated by the study team

2021-07-22

Who can join

Age: 55 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients undergoing hip hemiarthroplasty surgery for a displaced femoral neck fracture

You may not qualify if…

• History of hemophilia, history of deep vein thrombosis, history of pulmonary embolism, history of thrombophilia, history of chronic renal failure
• Patients with coronary ischemia (active or within the past calendar year), patients who have suffered a myocardial infarction, undergone percutaneous coronary intervention, undergone coronary artery bypass grafting, or undergone any revascularization procedure within the past calendar year
• Patients with active subarachnoid hemorrhage, acquired defective color vision, patients who sustained a pathologic fracture (fracture through a neoplastic lesion), or patients who are pregnant
• Patients with a known allergy to tranexamic acid
• Patients taking Warfarin, Dabigatran, Rivaroxaban, Apixaban, and Fresh Frozen Plasma

Where it is running

• University of Connecticut Health Center — Farmington, Connecticut, United States
• Saint Francis Hospital and Medical Center — Hartford, Connecticut, United States

Full record on ClinicalTrials.gov

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