Dilute Povidone-iodine Irrigation vs No Irrigation for Children With Acute, Perforated Appendicitis

Completed · Phase 2

Conditions studied: Acute, Perforated Appendicitis

In brief

The goal of this study is to compare the efficacy of PVI irrigation to no irrigation for decreasing postoperative intra-abdominal abscesses in children with perforated appendicitis. Additionally, this study aims to verify the safety profile of dilute PVI for intra-abdominal irrigation.

Key facts

Study ID

NCT02664220

Run by

The University of Texas Health Science Center, Houston

People needed

100

Starts

2016-04-01

Expected to finish

2018-03-01

Last updated by the study team

2019-04-17

Who can join

Age: 2 and older, up to 17. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Children who undergo an appendectomy for perforated appendicitis. (Appendicitis: Diagnosis is made intraoperatively by the surgeon. Diagnosis Method: The visualization of a gross defect in the appendiceal wall or the presence of intraperitoneal stool or a fecalith at the time of operation.)

You may not qualify if…

• Patients presenting with simple or gangrenous appendicitis
• Patients with a history of iodine sensitivity, thyroid disease or renal disease
• Patients undergoing interval or incidental appendectomy
• Patients/parents/legal guardians who are both non-English and non-Spanish speaking

Where it is running

• The University of Texas Health Science Center at Houston — Houston, Texas, United States

Full record on ClinicalTrials.gov

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