Cancer DNA Detection in Blood and Urine

Completed

Conditions studied: Prostate Cancer

In brief

This study is being conducted to collect and analyze biospecimens (blood and urine) and clinical data from patients with prostate cancer as well as healthy volunteers to better understand the differences between cancer cells and normal tissues with the goal of developing a better way to detect and track the treatment of prostate cancer. * These samples are being collected to conduct research to accomplish the goal of improving cancer therapies, biomarkers, and hopefully lead to more effective treatment of prostate cancer. * The samples that you are providing as a patient with prostate cancer will be used in future research. * Your biospecimens will be compared to the cancer and normal volunteer specimens from other participants to understand genetic differences between normal and cancer cells. Genetic material, including DNA and RNA, will be obtained from samples, stored, and used for evaluation. * Clinical information and samples will be collected and stored for ongoing research. This is a necessity because improved diagnosis, prognosis and treatment of cancer in the future depend upon the ongoing analysis of basic research findings and clinical outcomes. This type of research may improve the lives of future patients with cancer. Men between the ages of 18 and 100 with a diagnosis of cancer undergoing standard therapy with radiation may join.

Key facts

Study ID

NCT02657863

Run by

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

People needed

61

Starts

2014-11-01

Expected to finish

2023-04-01

Last updated by the study team

2025-12-23

Who can join

Age: 18 and older, up to 100. Sex: male. Healthy volunteers: accepted.

You may qualify if…

• Male older than or equal to 18 years of age, but not older than 100 years of age.
• Signed informed consent prior to initiation of any study-related procedures.
• Minorities are included in this protocol.
• Signed informed consent prior to initiation of any study-related

You may not qualify if…

• It is the enrolling study physician's discretion to decide if a patient is not fit enough to undergo procedures outlined in this protocol.
• Persons who are incarcerated are not eligible to participate.
• Women are not eligible.
• Persons incapable of providing informed consent are not eligible.
• Any person with a personal history of prior malignancy is not eligible
• Persons with an inherited cancer syndrome or a medical history suggestive of an inherited cancer syndrome are not eligible.

Where it is running

• Johns Hopkins SKCCC — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

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