Change In Diaphragmatic Thickness Predicts Extubation Success

Stopped early

Conditions studied: Mechanical Ventilation Complication

In brief

We will investigate whether measurement of the change in thickness of the diaphragm during the respiratory cycle by ultrasound can predict extubation success in a 48 hour window. We will also asses whether this is only possible on low levels of pressure support as has been shown previously, or if this technique retains its predictive power at higher levels of pressure support.

Key facts

Study ID

NCT02656199

Run by

Albert Einstein Healthcare Network

People needed

57

Starts

2015-01-01

Expected to finish

2017-01-13

Last updated by the study team

2020-03-09

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• age greater than 18, ventilated for >24 hours

You may not qualify if…

• already chronically on mechanical ventilatory support, already has tracheostomy, has pathology that obscures visualization of the right hemidiaphragm, has acute stroke either hemorrhagic or ischemic, cannot identify appropriate decision maker to get informed consent.

Where it is running

• Einstein Medical Center — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

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