Oxidative Stress in OR Personnel

Withdrawn before enrolling

Conditions studied: Oxidative Stress

In brief

The purpose of this study is investigate to the effect(s) of chronic occupational exposure to N20 and volatile anesthetics on the extent of oxidative stress (DNA damage and the generation of the biochemical markers) in operating room staff, with different levels of exposure to halogenated hydrocarbons, in comparison to unexposed controls (Intensive Care Staff), and to determine the relationship between the degree of oxidative stress and psychological stress, as assessed by validated psychometric measures.

Key facts

Study ID

NCT02654834

Run by

Nationwide Children's Hospital

People needed

0

Starts

2014-05-01

Expected to finish

2016-03-01

Last updated by the study team

2018-01-25

Who can join

Age: any. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• CHOR-Staff who work > 40 hours per week in the operating rooms (Anesthesiologists, CRNA, Surgeons, Nurses)
• NOR- Intensive Care Unit Staff who work > 40 hours per week in Intensive care unit (Physicians, Nurses, APN'S)

You may not qualify if…

• Staff with the following history will be excluded:
• Therapeutic exposure to radiation
• On chemotherapeutic agents
• History of General Anesthesia during the past two years

Where it is running

• Nationwide Children's Hospital — Columbus, Ohio, United States

Full record on ClinicalTrials.gov

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