Soft Tissue and Bone Development in Young Girls

Completed

Conditions studied: Bone Development

In brief

Obesity during adolescence, a critical time for bone development, may impair mineral accrual and reduce bone strength, leading to greater fracture risk during adolescence and later in life. This study seeks to determine the effect of obesity and accompanying metabolic changes (insulin resistance and inflammation) on bone mineral accrual and related changes in structure and strength in young girls. The information is critical to developing effective prevention strategies to counter the linked risks of obesity and osteoporosis, both major public health concerns.

Key facts

Study ID

NCT02654262

Run by

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

People needed

358

Starts

2013-01-01

Expected to finish

2018-12-31

Last updated by the study team

2026-05-11

Who can join

Age: 9 and older, up to 12. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• healthy, female, aged 9-12 years

You may not qualify if…

• diagnosis of diabetes
• taking medications that alter body composition and bone mineral accrual
• physical disability that limits physical activity
• learning disability that would limit completion of questionnaires

Where it is running

• University of Arizona, Nutritional Sciences Department — Tucson, Arizona, United States

Full record on ClinicalTrials.gov

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