Volatiles in Exhaled Breath and Blood in Crohn's Disease: Validation Cohort

Stopped early

Conditions studied: Crohn's Disease

In brief

This study evaluates the use of exhaled air analysis as tool to monitor the disease activity in Crohn's Disease (CD). This study is a validation of the previous findings. In this study the participant will be asked to donate exhaled air, blood samples and fecal samples. The breath samples will be used to measure various volatile metabolites in breath. The breath air will be next used to validate the previous findings. The blood samples will be used to define the origin of volatile metabolites in breath. Finally, the potential of exhaled breath analysis as non-invasive marker of diseases activity will be compared to established fecal calprotectin.

Key facts

Study ID

NCT02641171

Run by

Dartmouth-Hitchcock Medical Center

People needed

5

Starts

2015-12-01

Expected to finish

2016-10-04

Last updated by the study team

2018-07-12

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age: 18-65
• BMI: 19-30
• scheduled colonoscopy

You may not qualify if…

• disease compromising immune system (such as HIV positive status or patients after organ transplantation
• liver disease
• active and untreated tuberculosis
• chemotherapy agents

Where it is running

• Dartmouth Hitchcock Medical Center — Lebanon, New Hampshire, United States

Full record on ClinicalTrials.gov

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