Brain Response to Dietary Interventions
Completed · Not applicable
Conditions studied: Obesity
In brief
In order to better understand how commonly used dietary interventions for obesity influence brain activity and in turn people's ability to adhere to their healthy nutrition plan, the investigators need to study how people's brains react to food cues while undergoing such interventions. Our study will add to our understanding of neural (brain) regulation of hedonic and homeostatic mechanisms (i.e. pleasure and hunger) in influencing adherence to calorie-reduced eating plans.
Key facts
- Study ID
- NCT02637271
- Run by
- Texas Tech University
- People needed
- 32
- Starts
- 2016-01-01
- Expected to finish
- 2016-06-01
- Last updated by the study team
- 2016-09-02
Who can join
Age: 19 and older, up to 60. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age: 19-60 years
- BMI of 30-39.9 kg/m2 (upper limit due to scanner comfort/feasibility)
You may not qualify if…
- Participants unable to provide informed consent.
- Participants with motor, visual or hearing impairment.
- Females with irregular menstrual cycles.
- Patients currently diagnosed with diabetes mellitus, experiencing uncontrolled hypertension, history of ischemic heart disease, cerebrovascular accidents, neurological disease or current severe psychiatric illness (e.g. psychosis, schizophrenia, severe untreated depression, current suicidal ideation, and current or past suicide attempts), history of psychiatric hospitalization.
- Women who are pregnant or who are attempting to conceive.
- Participants with contraindications for fMRI scanning.
- aneurism clips
- any implanted medical devices (pacemaker, neurostimulator)
- known pregnancy
- shrapnel in body or any injury to eye involving metal
- any ferrous metal in body
- Participants with a history of eating disorders such as bulimia nervosa, anorexia nervosa and severe binge eating disorder.
- Participants with a history of substance abuse or alcohol abuse.
- Participants who are currently on or have been on within the past 4 weeks any anti-depressant, anti-epileptic, or anxiolytic medicines.
- Patients experiencing persistent loss of appetite, nausea or vomiting within the last 4 weeks.
- Participants who have been involved in a weight loss intervention program (including anti-obesity medication) within the past 3 months or who have had bariatric surgery.
- Current smokers (within the last 30 days).
Where it is running
- Texas Tech University - Department of Nutritional Sciences — Lubbock, Texas, United States
Full record on ClinicalTrials.gov
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