Effect of Neuromuscular Blockade on Pulmonary Complications in Elective Cardiac Surgery

Completed · Phase 4

Conditions studied: Neuromuscular Blockade, Postoperative Complications

In brief

The investigators will conduct a prospective, randomized trial to assess the impact of neuromuscular blockade on early (\<72 hours post-ICU admission) postoperative respiratory complications in cardiac surgical patients. The study will compare continual neuromuscular blockade with cisatracurium to a single dose of succinylcholine during general anesthesia for cardiac surgery.

Key facts

Study ID

NCT02635542

Run by

University of Chicago

People needed

100

Starts

2016-03-01

Expected to finish

2017-09-15

Last updated by the study team

2018-07-17

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Elective cardiac surgery (CABG, valve replacement, CABG + valve) requiring cardiopulmonary bypass

You may not qualify if…

• Emergency surgery
• Extremes of age
• Previous cardiac surgery
• Clinical contraindications to succinylcholine or cisatracurium
• Anticipated difficult tracheal intubation
• Preoperative mechanical ventilation
• Preoperative pharmacologic/mechanical hemodynamic support

Where it is running

• University of Chicago Medicine — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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