Impact of Duration Of Absolute Voice Rest on Voice Outcome After Phonomicrosurgery

Stopped early · Not applicable

Conditions studied: Benign Neoplasm of True Vocal Cords

In brief

Absolute voice rest is commonly prescribed after vocal fold surgery, also known as phonomicrosurgery, for benign vocal fold lesions. This is thought to decrease scarring of vocal folds, which could result in increasing tissue stiffness and limitations in optimal vocal outcome. Unfortunately there is no standardized protocol as to how long patients should rest their voice after phonomicrosurgery. To date, there are no studies in the literature directly comparing the impact of short-term and long-term voice rest on vocal fold healing and voice outcome after phonomicrosurgery.

Key facts

Study ID

NCT02634957

Run by

University of Pittsburgh

People needed

17

Starts

2016-01-01

Expected to finish

2020-01-31

Last updated by the study team

2020-04-15

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients with benign mid membranous vocal fold lesions such as the following:
• Polyps
• Cysts
• Sub-epithelial fibrous mass
• Undergoing elective phonomicrosurgery for vocal fold lesions, which involves microflap excision +/- truncation +/- steroid injection into the vocal folds.
• Age 18 and older

You may not qualify if…

• Patients with any of the following will be excluded from the study:
• Reinke's edema
• Active smokers
• Ligamentous mid membranous vocal fold lesions
• RRP (Recurrent Respiratory Papillomatosis)
• Dysplasia
• CIS (Carcinoma-in-situ)
• SCC (squamous cell carcinoma)
• Extent of surgery exceeds what is mentioned in the inclusion criteria (e.g., CO2 laser, balloon dilatation, vocal fold augmentation in addition to phonomicrosurgery)
• Previous vocal fold surgery
• Systemic steroids
• History of systemic illness that could affect wound healing

Where it is running

• University of Pittsburgh — Pittsburgh, Pennsylvania, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.