INtervention Study In overweiGHT Patients With COPD

Completed · Not applicable

Conditions studied: Pulmonary Disease, Chronic Obstructive, Obesity, Weight Loss, Life Style, Overweight

In brief

Symptoms of chronic obstructive pulmonary disease (COPD) and high body mass index (BMI) overlap. The investigators are trying to find out if a program proven to help people lose a modest amount of weight and increase their physical activity will improve COPD symptoms for those with a high BMI. The program uses a series of video sessions and self-study handouts focused on healthy eating and increasing physical activity, and encourages participants to monitor their weight, diet, and physical activity for one year. For those who want to, they will be able to work with a health coach to help meet weight and activity goals. We hope that the program will lead to improved exercise tolerance, body weight, dyspnea, generic health-related quality of life, and major cardiovascular risk factors (central obesity by waist circumference, Framingham Risk Score, and blood pressure) through 12 months of follow-up. To be in the study, participants will need to have COPD, high BMI, history of smoking, shortness of breath, and be at least 40 years old.

Key facts

Study ID

NCT02634268

Run by

Seattle Institute for Biomedical and Clinical Research

People needed

684

Starts

2017-05-12

Expected to finish

2020-10-30

Last updated by the study team

2022-04-07

Who can join

Age: 40 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 40 years or older at time of eligibility screening;
• Body mass index 25.0-44.9 kg/m2 (also see Figure 2);
• Smoked more than 10 pack-years of cigarettes;
• Shortness of breath;
• COPD;
• Able to participate fully in all study protocol/procedures including written informed consent process.

You may not qualify if…

• Inability to speak, read, or understand English;
• Active weight loss interventions;
• Expected weight loss because of alternate explanations, such as from illness;
• Unable to ambulate to weight scale for weight measurement;
• Safety and/or adherence concerns due to severe physical or mental health issues or life expectancy <18 months;
• Pregnant, lactating, or planning to become pregnant during the study period;
• Participation in other intervention studies.

Where it is running

• Birmingham VA Medical Center — Birmingham, Alabama, United States
• University of Alabama at Birmingham - UAB Lung Health Center — Birmingham, Alabama, United States
• University of Arizona — Tucson, Arizona, United States
• University of California, Los Angeles — Los Angeles, California, United States
• Universtiy of California, San Francisco — San Francisco, California, United States
• National Jewish Health — Denver, Colorado, United States
• Waterbury Pulmonary Associates — Waterbury, Connecticut, United States
• Sarasota Memorial Hospital — Sarasota, Florida, United States
• Northwestern University - Northwestern Medical Group - Pulmonology — Chicago, Illinois, United States
• University of Illinois, Chicago - Division of Pulmonay, Critical Care, Sleep & Allergy — Chicago, Illinois, United States
• University of Iowa — Iowa City, Iowa, United States
• Chest Medicine — South Portland, Maine, United States
• University of Maryland — Baltimore, Maryland, United States
• Johns Hopkins University - Pulmonary & Critical Care Medicine — Baltimore, Maryland, United States
• Boston VA Medical Center — Boston, Massachusetts, United States
• Baystate Health — Springfield, Massachusetts, United States
• University of Michigan - Division of Pulmonary & Critical Care Medicine — Ann Arbor, Michigan, United States
• Minneapolis VA Health Care System - Pulmonology — Minneapolis, Minnesota, United States
• Minnesota Health Partners — Saint Paul, Minnesota, United States
• St. Louis VA — St Louis, Missouri, United States
• Albany Medical College — Albany, New York, United States
• University of Buffalo — Buffalo, New York, United States
• Buffalo VA Medical Center — Buffalo, New York, United States
• NYU Winthrop — Mineola, New York, United States
• Duke University — Durham, North Carolina, United States

Full record on ClinicalTrials.gov

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